NOT REALLY BUT THE COURTS MAY CAVE "Can the federal government order a national quarantine?...the federal authority is limited to restricting the movement of anyone who "is reasonably believed to be infected with a quarantinable communicable disease." It's not at all certain how that would apply to large groups of people. Under the law, there is no explicit statutory authority for a blanket federal interstate quarantine, only for the isolation of individual people deemed infected."
https://www.nbcnews.com/politics/politics-news/can-federal-government-order-national-quarantine-n1162036 